Intestinal Hyperpermeability Syndrome
The contents of the intestinal lumen must be eliminated outside the body so that toxic waste and antigens do not join the blood flow which would bring them to the different tissues and organs.
This protection due to the impermeability of the intestinal wall, involves inter-dependent mechanisms: intestinal secretions, mainly mucus and secretory IgA, the epithelial mucosa and lymphocytes.
Any attack on the function of intestinal barrier increases the production of oxidants and carcinogens and can cause infectious and inflammatory bowel diseases, chronic inflammatory rheumatism, skin damage (acne, psoriasis, dermatitis herpetiformis), immune deficiency, chronic fatigue syndrome, chronic hepatitis, chronic pancreatitis, pancreatic carcinoma...
Causes of hyperpermeability: bacterial endotoxins, membrane polymers, dietary gluten
Triggers: infectious agents (viral, bacterial, protozoa), alcohol, non-steroidal anti-inflammatories, cytotoxic drugs (chemotherapy), high levels of oxidative metabolites (biliary, of food origin or produced by inflammatory cells).
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